FGR Antibody / c-FGR proto oncogene

FGR Antibody / c-FGR proto oncogene

• Description: FGR is a member of the Src family of protein tyrosine kinases (PTKs). This protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. It localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this protein.
• CAS Number: 9007-83-4
• UniProt: P09769
• Host: Rabbit
• Immunogen: A portion of amino acids 3-33 from the human protein was used as the immunogen for the FGR antibody.
• Clonality: Polyclonal
• Isotype: Ig
• Applications: IF, IHC-P, WB
• Format: Purified
• Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Reconstitution: Aliquot the FGR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This FGR antibody is available for research use only.