Products for Research Use Only
RegisterLogin

BRAF35 Polyclonal Antibody

CAT: 0965-JOT-AP00964-01Size: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0965-JOT-AP00964-01Size:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q. Mutations within this gene account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer. A second breast cancer susceptibility gene, BRCA2, located on chromosome 13q12-13, also confers a high incidence of breast cancer, but unlike BRCA1, BRCA2 does not confer a substantially elevated risk of ovarian cancer. The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2, which associates with condensed chromatin during histone H3 phosphorylation. BRAF35 expression levels are highest in proliferating tissues and parallel BRCA2 expression patterns. The structure of BRAF35 includes a kinesin-like coiled coil domain and a nonspecific DNA binding HMG domain. The chromatin localization of BRAF35 and antibody microinjection studies indicate a role for the BRAF35/BRCA2 complex in cell cycle regulation.
CAS Number
9007-83-4
Synonyms
HMG20B; BRAF35; HMGX2; HMGXB2; SMARCE1R; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related; SMARCE1-related protein; BRCA2-associated factor 35; HMG
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human HMG20B. AA range:1-50
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
35813
Antibody Type
Primary antibody
Isotype
IgG

Related Products

CatalogName
JOT-AP15592-01YTHD2 Polyclonal Antibody
JOT-AP15626-01ZEB1 Polyclonal Antibody
JOT-AP15515-01VWA3A Polyclonal Antibody
JOT-AP15563-01WWTR1 Polyclonal Antibody
JOT-AP15568-01XDH Polyclonal Antibody
JOT-AP15664-01ZN713 Polyclonal Antibody
JOT-AP15660-01ZN574 Polyclonal Antibody
JOT-AP15554-01WNT7B Polyclonal Antibody
JOT-AP15651-01ZN281 Polyclonal Antibody
JOT-AP15702-01ZNRF1 Polyclonal Antibody

Alternative Products

CatalogName
MBS8521496-01BRAF35 Polyclonal Antibody
NBP2-58321-25ulRabbit Polyclonal BRAF35 Antibody
APRab07639-01BRAF35 Rabbit Polyclonal Antibody
TMAB-03202-01Anti-BRAF35 Polyclonal Antibody
C40653BRAF35 Polyclonal Conjugated Antibody

Popular Products