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BMP-8 Polyclonal Antibody

CAT: 0965-JOT-AP00931-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP00931-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BMP8B (bone morphogenetic protein 8b) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of BMP8B may be downregulated in pancreatic cancer. BMP8B may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1.
CAS Number
9007-83-4
Synonyms
BMP8B; BMP8; Bone morphogenetic protein 8B; BMP-8; BMP-8B; Osteogenic protein 2; OP-2; BMP8A; Bone morphogenetic protein 8A; BMP-8A
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human BMP-8. AA range:41-90
Clonality
Polyclonal
Applications
IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
44768
Antibody Type
Primary antibody
Isotype
IgG

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