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BMP-6 Polyclonal Antibody

CAT: 0965-JOT-AP00928-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP00928-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BMP6 (bone morphogenetic protein 6) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of BMP6 may be associated with progression of breast and prostate cancer. Mutations in BMP6 may be associated with iron overload in human patients.
CAS Number
9007-83-4
Synonyms
BMP6; VGR; Bone morphogenetic protein 6; BMP-6; VG-1-related protein; VG-1-R; VGR-1
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human BMP-6. AA range:103-152
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
57226
Antibody Type
Primary antibody
Isotype
IgG

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