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BCAR3 Polyclonal Antibody

CAT: 0965-JOT-AP00851-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP00851-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. BCAR3 (breast cancer anti-estrogen resistance 3) encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for BCAR3.
CAS Number
9007-83-4
Synonyms
BCAR3; NSP2; SH2D3B; Breast cancer anti-estrogen resistance protein 3; Novel SH2-containing protein 2; SH2 domain-containing protein 3B
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human BCAR3. AA range:761-810
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
92566
Antibody Type
Primary antibody
Isotype
IgG

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