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Aven Polyclonal Antibody

CAT: 0965-JOT-AP00771-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP00771-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
AVEN, a cell death regulator, is an important signal inducer in acute leuke-mias. AVEN is a highly conserved peripheral membrane protein that protects the cell against the proteolytic activation of caspases as well as Apaf-1 mediated apoptosis by interfering with Apaf-1's ability to self-associate. Bcl-2 and Bad also interact with AVEN to prevent apoptosis. AVEN is highly expressed in ovary, heart, thymus, spleen, testis and colon, but can also be detected in other tissues. Erythropoietin and methylprednisolone may play important roles in the expression of AVEN in cardiac tissue, especially after a traumatic brain injury. In young patients suffering from acute lymphoblastic leukemia (ALL), AVEN expression may be a useful tool in prognosis prediction.
CAS Number
9007-83-4
Synonyms
AVEN; Cell death regulator Aven
Host
Rabbit
Reactivity
Human;Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human AVEN. AA range:301-350
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
38506
Antibody Type
Primary antibody
Isotype
IgG

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