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Arkadia Polyclonal Antibody

CAT: 0965-JOT-AP00614-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP00614-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by RNF111 (ring finger protein 111) is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF)-beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, RNF111 plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of RNF111 results in multiple transcript variants encoding distinct isoforms.
CAS Number
9007-83-4
Synonyms
RNF111; E3 ubiquitin-protein ligase Arkadia; RING finger protein 111
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human RNF111. AA range:901-950
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
108876
Antibody Type
Primary antibody
Isotype
IgG

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