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APPL1 Polyclonal Antibody

CAT: 0965-JOT-AP00546-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP00546-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by APPL1 has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1) binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
CAS Number
9007-83-4
Synonyms
APPL1; APPL; DIP13A; KIAA1428; DCC-interacting protein 13-alpha; Dip13-alpha; Adapter protein containing PH domain; PTB domain and leucine zipper motif 1
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human APPL1. AA range:121-170
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
79663
Antibody Type
Primary antibody
Isotype
IgG

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