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CYTSA rabbit pAb

CAT: 0855-ES17031-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES17031-01Size:50 µL
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Background
This gene encodes a coiled-coil domain containing protein. The encoded protein may play a critical role in actin-cytoskeletal reorganization during facial morphogenesis. Mutations in this gene are a cause of oblique facial clefting-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A read-through transcript composed of SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and the downstream ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013]
Description
This gene encodes a coiled-coil domain containing protein. The encoded protein may play a critical role in actin-cytoskeletal reorganization during facial morphogenesis. Mutations in this gene are a cause of oblique facial clefting-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A read-through transcript composed of SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and the downstream ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013],
UniProt
Q69YQ0
Swiss Prot
Q69YQ0
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human CYTSA AA range: 150-200
Target
CYTSA
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, spindle . Cell junction, gap junction . Colocalizes with acetylated alpha-tubulin, gamma-tubulin and F-actin. Also observed in a ring around gamma-tubulin containing centrioles possibly in the microtubule organizing center.
Gene ID (Human)
23384

UniProtKB · Q69YQ0

Cytospin-A

CYTSA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q69YQ0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SPECC1L
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B7Z758, F5H1H6, O15081
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

Cell cycleCell division

Cellular component

Cell junctionCytoplasmCytoskeletonGap junction

Domain

Coiled coil

Disease

Disease variant

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

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