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Elemicin

CAT: 0804-HY-N6807Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N6807Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Elemicin is an orally active alkenylbenzene widely distributed in many herbs and spices. Elemicin inhibits Stearoyl-CoA Desaturase 1 (SCD1) by metabolic activation. Elemicin has anti-influenza activities, antimicrobial, antioxidant, and antiviral activities. Elemicin and its reactive metabolite of 1′-Hydroxyelemicin can induce hepatotoxicity[1][2][3][4].
CAS Number
487-11-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial; Influenza Virus; Stearoyl-CoA Desaturase (SCD)
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/elemicin.html
Purity
98.02
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C=CCC1=CC(OC)=C(OC)C(OC)=C1
Molecular Formula
C12H16O3
Molecular Weight
208.25
Precautions
H302, H315, H319, H335
References & Citations
[1]Yang XN, et al. Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1. Chem Res Toxicol. 2019 Sep 10.|[2]Yi-Kun Wang, et al. Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity. J Agric Food Chem. 2019 Jul 24;67 (29) :8243-8252.|[3]Xiao-Nan Yang, et al. Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1. Chem Res Toxicol. 2019 Oct 21;32 (10) :1965-1976.|[4]Ayodeji Oluwabunmi Oriola, et al. Essential Oils and Their Compounds as Potential Anti-Influenza Agents. Molecules. 2022 Nov 12;27 (22) :7797.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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