CD331 Recombinant Protein

CAT: 0384-NCP0321-01Size: 500 µgDry Ice: NoHazardous: No
CAT#:0384-NCP0321-01Size:500 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through cell surface receptor tyrosine kinases. There are four members of the FGF receptor family: FGFR1 (flg), FGFR2 (bek, KGFR), FGFR3, and FGFR4. Each receptor contains an extracellular ligand binding domain, a transmembrane domain, and a cytoplasmic kinase domain. Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues. Seven tyrosine residues in the cytoplasmic tail of FGFR1 can be phosphorylated: Tyr463, 583, 585, 653, 654, 730, and 766. Tyr653 and Tyr654 are important for catalytic activity of activated FGFR and are essential for signaling. The other phosphorylated tyrosine residues may provide docking sites for downstream signaling components such as Crk and PLCγ.
CAS Number
9000-83-3
Swiss Prot
P11362
Modification Site
NdeI-XhoI
Expression System
Pet-22b (+)
Tag
His-tag
Purity
Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE) .
Solubility
PBS, 4M Urea, PH7.4
Molecular Weight
~48kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Host or Source
E.coli
AA Sequence
RPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRI TGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKET DNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDH RIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGL PANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDK EMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLE

Related Products

CatalogName
NCP0296-01CD336 Recombinant Protein
NCP0298-01CD338 Recombinant Protein
NCP0301-01CD351 Recombinant Protein
NCP0309-01CD361 Recombinant Protein
NCP0318-01CD335 Recombinant Protein
NCP0316-01CD321 Recombinant Protein
NCP0297-01CD337 Recombinant Protein
NCP0385-01CD301 Recombinant Protein
NCP0361-01CD334 Recombinant Protein
NCP0351-01CD33 Recombinant Protein

Alternative Products

CatalogName
E43CP0321CD331 Recombinant Protein
TD-ATMP00474HURecombinant Human CD331 protein
PPT-11507Human CD331/FGFR1 Recombinant Protein
MBS9146786-01Recombinant Mouse FGFR-1/CD331 Protein
MBS9144058-01Recombinant human FGF R1/CD331 Protein
MBS2546161-01Recombinant Human FGFR1 / CD331 Protein (His tag)
YHC88101Recombinant Human CD331/FGFR1 Protein, N-His
PKSM040821Recombinant Mouse FGFR1/CD331 Protein (His Tag)
PKSM040822Recombinant Mouse FGFR1/CD331 Protein (Fc Tag)
E40KMH472Recombinant Human CD331/FGFR1 Protein, His Tag

Popular Products