Products for Research Use Only
RegisterLogin

RecombinantIFN-γ, Human (CHO-expressed)

CAT: 0384-BK0223-01Size: 10 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BK0223-01Size:10 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Human Interferon gamma (hIFN-γ) is amacrophage-activating factor and the lone member of Interferon type II. The active form of IFN-γ is an antiparallel dimer that interacts with the receptor IFN-γR1 and sets off IFN-γ/JAK/STAT pathway. IFN-γ signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity. While IFN-γ–induced inflammatory cascade summons a variety of immune-related cell types, such as macrophages, natural killer (NK) cells and cytotoxic T lymphocytes (CTLs), IFN-γ is also implicated in resistance to NK cell and CTL responses and in immune escape in a variety of cancers.
CAS Number
9000-83-3
Endotoxin
< 0.2 EU/μg, determined by LAL method.
Purity
> 95% as analyzed by SDS-PAGE and HPLC.
Bioactivity
ED50 < 2 ng/ml, measured in a cytotoxicity assay using HT-29 cells, corresponding to a specific activity of > 5x10ˆ5 units/mg.
Reconstitution
Reconstituted in ddH2O or PBS at 100 μg/ml.
Molecular Weight
15-25 kDa, observed by non-reducing SDS-PAGE.
Storage Conditions
Lyophilized recombinant Human Interferon gamma (IFN-γ) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rh IFN-γ should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized after extensive dialysis against PBS.
Host or Source
CHO
Recommended Usage
This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.
AA Sequence
QDPYVKEAENLKKYFNAGHSDVADNGTLFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVK FFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKTGKRKRSQMLFRGRRASQ

Related Products

CatalogName
BK0224-01RecombinantIFN-γ, Rat (CHO-expressed)
BK0253-01RecombinantIL-6, Human (CHO-expressed)
BK0228-01RecombinantIL-11, Human (CHO-expressed)
BK0232-01RecombinantIL-13, Human (CHO-expressed)
BK0249-01RecombinantIL-5, Human (CHO-expressed)
BK0238-01RecombinantIL-1β, Human (CHO-expressed)
BK0243-01RecombinantIL-3, Human (CHO-expressed)
BK0225-01RecombinantIL-10, Human (CHO-expressed)
BK0255RecombinantIL-7, His, Human (CHO-expressed)
BK0221-01RecombinantI-309/CCL1, Human (CHO-expressed)

Alternative Products

CatalogName
BK0223RecombinantIFN-γ,Human(CHO-expressed)
GTR18990319-01RecombinantIFN-γ, Human (CHO-expressed)
BK0224RecombinantIFN-γ,Rat(CHO-expressed)
GTR18990318-01RecombinantIFN-γ, Rat (CHO-expressed)
GTR18990236-01RecombinantIFN-β, Human
BK0307RecombinantIFN-β,Human
BK0080RecombinantIFN-γ,Human
GTR18990536-01RecombinantIFN-γ, Human
Z03005-50GH, Human (CHO-expressed)
Z02986-10IFN-γ, Human (CHO-expressed)

Popular Products