Products for Research Use Only
RegisterLogin

RecombinantIGF-I, Mouse

CAT: 0384-BK0085-01Size: 10 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BK0085-01Size:10 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Insulin-like Growth Factor I (IGF-I) is a single chain 7 kDa growth-promoting polypeptide originally identified as somatomedin-c. It belongs to the IGF family of peptides, which also includes IGF-II and insulin. The gene expression of IGF-I is mainly regulated by Growth Hormone, and IGF-I executes its functions via signaling through transmembrane tyrosine receptors (IGF Receptors) . Most circulating IFG-I is associated with the IGF Binding Protein 3 (IGFBP-3), and the IGFBPs may inhibit the actions of IGFs by competing against the IGF Receptors. IGF-I is active in post-natal and adult animals, and is crucial for somatic growth, as IGF-I null mice show marked retardation in utero. IGF-I is involved in carcinogenesis, and related to prostate cancer as well.Recombinant mouse Insulin-like Growth Factor I (rmIGF-I) produced in E. coli is a single non-glycosylated polypeptide chain containing 71 amino acids. A fully biologically active molecule, rmIGF-I has a molecular mass of 7.8kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
CAS Number
9000-83-3
Endotoxin
< 0.2 EU/μg, determined by LAL method.
Purity
> 95% by SDS-PAGE analysis.
Bioactivity
ED50 <10ng/mL, measured by a cell proliferation assay using FDC-P1 cells, corresponding to a specific activity of >1x10ˆ5 units/mg.
Reconstitution
Reconstituted in ddH2O at 100 μg/mL.
Molecular Weight
7.8 kDa, observed by reducing SDS-PAGE.
Storage Conditions
Lyophilized recombinant mouse Insulin-like Growth Factor I (rmIGF-I) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rmIGF-I remains stable up to 2 weeks at 4°C or up to 3 months at -20°C.
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized after extensive dialysis against PBS.
Host or Source
Escherichia coli.
Recommended Usage
This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.
AA Sequence
MGPETLCGA ELVDALQFVC GPRGFYFNKP TGYGSSIRRA PQTGIVDECC FRSCDLRRLE MYCAPLKPTK AA

Related Products

CatalogName
BK0084-01RecombinantIGF-I, Human
BK0086-01RecombinantIGF-I, Rat
BK0083-01RecombinantIGF-I (N-Met), Human
BK0087-01RecombinantIGF-II, Human
BK0309-01RecombinantIGF-BP-4, His, Human
BK0308-01RecombinantIGF-BP-2, His, Human
BK0027-01RecombinantEGF, Mouse
BK0081-01RecombinantIFN-γ, Mouse
BK0122-01RecombinantLIF, Mouse
BK0134-01RecombinantMIF, Mouse

Alternative Products

CatalogName
GTR18990530-01RecombinantIGF-I, Mouse
BK0085RecombinantIGF-I,Mouse
MBS9472251-01FITC anti-mouse I-A/I-E
MBS9472131-01APC anti-mouse I-A/I-E
GT01505PE anti-mouse I-A/I-E
GT01499Purified anti-mouse I-A/I-E
GT01519PerCP anti-mouse I-A/I-E
GT01500Biotin anti-mouse I-A/I-E
GTR18716501-01PE mouse I-A/I-E Antibody
GTR18715811-01APC mouse I-A/I-E Antibody

Popular Products