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PCSK1 Recombinant Rabbit mAb

CAT: 0384-BS49327-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS49327-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. The protease is packaged into and activated in dense core secretory granules and expressed in the neuroendocrine system and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It functions in the proteolytic activation of polypeptide hormones and neuropeptides precursors. Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene [provided by RefSeq, Jan 2014]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
PC1; PC3; NEC1; SPC3; PC1/3; BMIQ12
Swiss Prot
P29120, P63239, P28840
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human PCSK1
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, FC, IP
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
70 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of extracts from Mouse small intestine tissue using BS49327 at 1: 1000.
Host or Source
Rabbit

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