Products for Research Use Only

Caspase-4 Recombinant Rabbit mAb

CAT: 0384-BS49207-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS49207-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
TX; Mih1; ICH-2; Mih1/TX; ICEREL-II; ICE (rel) II
Swiss Prot
P49662
Reactivity
Human
Immunogen
Recombinant protein of human Caspase-4
Conjugation
Unconjugated
Applications
WB, FC
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
45 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of extracts from THP-1 cells at 1:1000.
Host or Source
Rabbit