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Nuclear Factor Erythroid Derived 2 Recombinant Rabbit mAb

CAT: 0384-BS48145-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS48145-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR) . This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
P45; NF-E2
Swiss Prot
Q16621
Reactivity
Human
Immunogen
Recombinant protein of human Nuclear Factor Erythroid Derived 2
Conjugation
Unconjugated
Applications
WB, IHC, FC
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
42 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of extracts from K562 cells using BS48145 at 1: 1000.
Host or Source
Rabbit

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