CD137 Recombinant Rabbit mAb

• Background :

  The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]

• Structure Composition :

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative :

  ILA; 4-1BB; CD137; CDw137

• Swiss Prot :

  Q07011

• Reactivity :

  Human

• Immunogen :

  Recombinant protein of human CD137

• Conjugation :

  Unconjugated

• Applications :

  WB

• Dilution :

  WB: 1:1000

• Purity :

  Affinity Purification

• Modification :

  Unmodification

• Molecular Weight :

  36-40 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  IgG

• Host or Source :

  Rabbit

• CAS Number :

  9000-83-3