PPAR delta Recombinant Rabbit mAb

• Background:

  This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. The encoded protein is thought to function as an integrator of transcriptional repression and nuclear receptor signaling. It may inhibit the ligand-induced transcriptional activity of peroxisome proliferator activated receptors alpha and gamma, though evidence for this effect is inconsistent. Expression of this gene in colorectal cancer cells may be variable but is typically relatively low. Knockout studies in mice suggested a role for this protein in myelination of the corpus callosum, lipid metabolism, differentiation, and epidermal cell proliferation. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Aug 2017]

• Structure Composition:

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative:

  FAAR; NUC1; NUCI; NR1C2; NUCII; PPARB

• Swiss Prot:

  Q03181

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human PPAR delta

• Conjugation:

  Unconjugated

• Applications:

  WB, IP

• Purity:

  Affinity Purification

• Modification:

  Unmodification

• Molecular Weight:

  50 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of extracts from Rat heart tissue at 1:1000.

• Host or Source:

  Rabbit

• CAS Number:

  9000-83-3