PPAR alpha Recombinant Rabbit mAb

• Background :

  Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]

• Structure Composition :

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative :

  PPAR; NR1C1; hPPAR; PPARalpha; PPAR-alpha

• Swiss Prot :

  Q07869

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant protein of human PPAR alpha

• Conjugation :

  Unconjugated

• Applications :

  WB

• Dilution :

  WB: 1:1000

• Purity :

  Affinity Purification

• Modification :

  Unmodification

• Molecular Weight :

  52 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  IgG

• Applications Notes :

  Western blot analysis of extracts from HepG2 cells using it at 1:1000.

• Host or Source :

  Rabbit

• CAS Number :

  9000-83-3