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Munc 13-4 Recombinant Rabbit mAb

CAT: 0384-BS45909-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS45909-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq, Jul 2008]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
FHL3; HLH3; HPLH3; Munc13-4
Swiss Prot
Q70J99
Reactivity
Human, Mouse
Immunogen
A synthetic peptide of human Munc 13-4
Conjugation
Unconjugated
Applications
WB, FC
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
123 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of extracts from K562 cells using BS45909 at 1: 1000.
Host or Source
Rabbit

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