CD41 Recombinant Rabbit mAb

• Background :

  Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

• Structure Composition :

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative :

  CD41; CD41B; GpIIb; AI172977; alphaIIb

• Swiss Prot :

  Q9QUM0

• Reactivity :

  Mouse, Rat

• Immunogen :

  Recombinant protein of mouse CD41

• Conjugation :

  Unconjugated

• Applications :

  WB, IHC

• Purity :

  Affinity Purification

• Modification :

  Unmodification

• Molecular Weight :

  113 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  IgG

• Applications Notes :

  Western blot analysis of extracts from Mouse spleen tissue at 1:1000.

• Host or Source :

  Rabbit

• CAS Number :

  9000-83-3