AURKC polyclonal antibody

• Background :

  This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

• Structure Composition :

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  AURKC; AIE2; AIK3; ARK3; AurC; HEL-S-90; SPGF5; STK13; aurora-C

• Swiss Prot :

  Q9UQB9

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthetic peptide of human AURKC (NP_001015878.1) .

• Conjugation :

  Unconjugated

• Applications :

  WB, IHC

• Dilution :

  WB,1:500 - 1:2000|IHC,1:50 - 1:100

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  36kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  Polyclonal Antibodies

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4