Products for Research Use Only

AURKA (P282) polyclonal antibody

CAT: 0384-BS1612-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS1612-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Aurora kinase A; Aurora 2; Aurora/IPL1-related kinase 1; ARK-1; Aurora-related kinase 1; hARK1; Breast tumor-amplified kinase; Serine/threonine-protein kinase 15; Serine/threonine-protein kinase 6; Serine/threonine-protein kinase aurora-A; AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Swiss Prot
O14965
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 251-300 of Human AURKA.
Conjugation
Unconjugated
Related Pathways
Epigenetic Writers and Erasers of Histone H3
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 46 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
AURKA (P282) polyclonal antibody detects endogenous levels of AURKA protein.
Applications Notes
Western blot (WB) analysis of AURKA (P282) polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate (40ug) Lane2:HepG2 whole cell lysate (40ug) Lane3:L02 whole cell lysate (40ug) Lane4:C6 whole cell lysate (40ug) Lane5:BV2 whole cell lysate (40ug)
Host or Source
Rabbit