NRF2 polyclonal antibody

• Background:

  This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.

• Structure Composition:

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  NFE2L2; HEBP1; NRF2

• Swiss Prot:

  Q16236

• Reactivity:

  Human, Mouse, Rat, Pig

• Immunogen:

  KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human NRF2.

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, IF/ICC

• Dilution:

  WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF/ICC,1:100 - 1:500

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodified

• Molecular Weight:

  110KDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  NRF2 polyclonal antibody detects endogenous levels of NRF2 protein.

• Applications Notes:

  Western blot analysis of NRF2 expression in HEK293T (A), A549 (B) whole cell lysates.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4