ELF3 polyclonal antibody

• Background :

  ESE-1, a member of the Ets family of transcription factors, critically regulates epithelial cell differentiation and mediates vascular inflammation. ESE-1 is strongly expressed in vascular endothelium and smooth muscle cells where it is induced in response to inflammatory cytokines and lipopolysaccharides, interacts with NF-KappaB to induce nitric oxide synthase, and is induced during terminal differentiation of epidermal and primary keratinocytes. In addition, ESE-1 is upregulated upon differentiation of corneal epithelium and interacts with Sp1 and AP-1 proteins to induce squamous differentiation marker expression in bronchial epithelial cells.

• Structure Composition :

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  ETS-related transcription factor Elf-3; E74-like factor 3; Epithelial-restricted with serine box; Epithelium-restricted Ets protein ESX; Epithelium-specific Ets transcription factor 1; ESE-1; ELF3; ERT; ESX; JEN

• Swiss Prot :

  P78545

• Reactivity :

  Human, Rat

• Immunogen :

  Recombinant full length Human ELF3.

• Conjugation :

  Unconjugated

• Applications :

  WB IHC IF

• Dilution :

  WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  ~ 41 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  ELF3 polyclonal antibody detects endogenous levels of ELF3 protein.

• Applications Notes :

  WesternBlot (WB) analysis of ELF3 polyclonal antibody

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4