PDCD10 polyclonal antibody

CAT: 0384-BS7439-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS7439-01Size:50 µL
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Background
This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
CCM3; TFAR15; PDCD10
Swiss Prot
Q9BUL8
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human PDCD10.
Conjugation
Unconjugated
Applications
WB, IHC-P, IF/ICC
Dilution
WB,1:500 - 1:1000|IHC-P,1:50 - 1:200|IF/ICC,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~25 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
PDCD10 polyclonal antibody detects endogenous levels of PDCD10 protein.
Applications Notes
Western blot analysis of various lysates, using PDCD10 pAb at 1:500 dilution.
Host or Source
Rabbit

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