PDCD1 polyclonal antibody

CAT: 0384-BS60383-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS60383-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
PDCD1 (Programmed Cell Death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. Pdcd-1 contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) within the cytoplasmic domain, which is conserved between the mouse and human homologs. Expression of Pdcd-1 is detected in mouse thymus, and it is induced in stimulated B and T cell lines, where it may play a role in the negative regulation of various immune responses. Receptors such as Pdcd-1 function by recruiting tyrosine phosphatases, including SHP-1 and SHIP, which are responsible for altering various B cell responses. Additionally, in activated lymphocytes, Pdcd-1 mediates the activation of the classical type of programmed cell death.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Programmed cell death protein 1; Protein PD-1; hPD-1; CD279; PD1
Swiss Prot
Q15116
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human PDCD1.
Conjugation
Unconjugated
Related Pathways
Immune checkpoint signaling in the Tumor Microenvironment, Tumor-Infiltrating Immune Cell Marker Guide, T cell receptor signaling
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 32 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
PDCD1 polyclonal antibody detects endogenous levels of PDCD1 protein.
Applications Notes
Western blot (WB) analysis of PDCD1 polyclonal antibody at 1:500 dilution Lane1:HepG2 cell lysate Lane2:Mouse liver tissue lysate Lane3:H9C2 cell lysate
Host or Source
Rabbit

Related Products

CatalogName
PPL00464-5aPX458-PDCD1
PPL00464PCR4-TOPO-PDCD1
PPL00464-4aPLenti-CMV-Puro-PDCD1
BS74753-01PDCD7 polyclonal antibody
BS91038PDCD4 polyclonal antibody
BS7439-01PDCD10 polyclonal antibody
BS7192-01PDCD4 polyclonal antibody
BS8821-01PDCD5 polyclonal antibody
BS78170PDCD4 polyclonal antibody
BS76234-01PDCD2 polyclonal antibody

Alternative Products

CatalogName
A60198-050PDCD1 Polyclonal Antibody
APR05453GPolyclonal PDCD1 Antibody
BT-AP04078-01PDCD1 Rabbit Polyclonal Antibody
GWB-BBP552Polyclonal Anti-PDCD1 Antibody
TA306403PD1 (PDCD1) Rabbit Polyclonal Antibody
A60199-100PDCD1 Polyclonal Antibody, Biotin Conjugated
ANT-11046-100ugCD279 / PDCD1 / PD1 Polyclonal Antibody
E55A02947CD279/PDCD1/PD1 Polyclonal Antibody
APR00377GPolyclonal PD-1/PDCD1 Antibody
A60200-050PDCD1 Polyclonal Antibody, FITC Conjugated

Popular Products