TRPC1 polyclonal antibody

• Background :

  Human TRPC1 protein is a 793 amino acid cation channel that is expressed in fetal and adult brain, and adult heart, testis and ovary, where it may influence store-operated Ca2+ entry as a component of capacitative calcium entry (CCE) complexes. The activation of store-mediated Ca2+ entry in human cells occurs through the association between inositol 1,4,5-trisphosphate receptors and TRPC1.

• Structure Composition :

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  Short transient receptor potential channel 1; TrpC1; Transient receptor protein 1; TRP-1; TRP1

• Swiss Prot :

  P48995

• Reactivity :

  Human, Mouse

• Immunogen :

  A synthetic peptide of human TRPC1.

• Conjugation :

  Unconjugated

• Applications :

  WB IHC

• Dilution :

  WB 1:500 - 1:2000 IHC 1:50 - 1:200

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  ~ 91 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  TRPC1 polyclonal antibody detects endogenous levels of TRPC1 protein.

• Applications Notes :

  Western blot analysis of extracts of various cell lines, using TRPC1 antibody at 1:1000 dilution.

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4