ORC4 polyclonal antibody

• Background :

  The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.

• Structure Composition :

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  ORC4L; ORC4P

• Swiss Prot :

  O43929

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant protein of human ORC4.

• Conjugation :

  Unconjugated

• Applications :

  WB

• Dilution :

  WB 1:500 - 1:2000

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodified

• Molecular Weight :

  ~ 50 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  ORC4 polyclonal antibody detects endogenous levels of ORC4 protein.

• Applications Notes :

  Western blot analysis of ORC4 expression in Hela (A), HepG2 (B), MCF7 (C) whole cell lysates.

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4