CEP170 polyclonal antibody

CAT: 0384-BS61661-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS61661-01Size:50 µL
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Background
Centrosomal protein 170kDa, also known as CEP170, is a protein that in humans is encoded by the CEP170 geneThe product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with the intraflagellar transport protein 81 (IFT81), the SH3-domain containing protein PRAX-1, and is phosphorylated by cyclin dependent kinase 1 (Cdk1) and polo-like kinase 1 (PLK1), and functions in maintaining Microtubule organization, cell morphology and cilium stability.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Centrosomal protein of 170 kDa; Cep170; KARP-1-binding protein; KARP1-binding protein; CEP170; FAM68A; KAB; KIAA0470
Swiss Prot
Q5SW79
Reactivity
Human
Immunogen
Synthetic peptide, corresponding Human CEP170.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 175 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CEP170 polyclonal antibody detects endogenous levels of CEP170 protein.
Applications Notes
Western blot (WB) analysis of CEP170 polyclonal antibody at 1:500 dilution Lane1:L02 whole cell lysate (40ug) Lane2:HEK293T whole cell lysate (40ug) Lane3:A549 whole cell lysate (40ug)
Host or Source
Rabbit

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