APLN polyclonal antibody

CAT: 0384-BS60997-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS60997-01Size:50 µL
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Background
Apelin (APEL), an endogenous ligand for APJ, is an alternate coreceptor with CD4 for HIV-1 infection. This secreted protein inhibits HIV-1 entry into cells that coexpress APJ and CD4. By proteolytic processing of the peptide precursor, several different active peptides may be produced. Apelin-36, one such inotropic peptide, is being investigated as a potential plasma marker of cardiopulmonary disease. Apelin is highly expressed in brain, mainly in the thalamus, frontal cortex, hypothalamus and midbrain. Apelin is also secreted by the mammary gland into the colostrum and milk. Oral intake of apelin (in milk and colostrum) may be important in the modulation of the immune responses in neonates and newborns. Apelin has also been found to be a potent stimulator of cardiac contractility and may function in the regulation of the cardiovascular system.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Apelin; APJ endogenous ligand; Apelin-36; Apelin-31; Apelin-28; Apelin-13; APLN; APEL
Swiss Prot
Q9ULZ1
Reactivity
Human
Immunogen
A synthetic peptide corresponding to residues in Human APLN.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 9 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
APLN polyclonal antibody detects endogenous levels of APLN protein.
Applications Notes
Western blot (WB) analysis of APLN polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:HELA whole cell lysate
Host or Source
Rabbit

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