Products for Research Use Only
RegisterLogin

ATXN7L2 polyclonal antibody

CAT: 0384-BS60708-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS60708-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
SCA7 is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss caused by the expansion of a translated CAG repeat encoding a polyglutamine tract in ataxin-7, which is the SCA7 gene product. Ataxin-7 is a nuclear protein that is expressed within neurons both affected and unaffected in SCA7 pathology with subcellular localization being variable depending upon the neuronal subtype. Polyglutamine expanded in ataxin-7 may carry out its pathogenic effects in the nucleus by altering the matrix-associated nuclear structure and/or by disrupting nucleolar function.ATXN7L2 (Ataxin-7-like protein 2) is a 722 amino acid protein that contains a SCA7 domain, which is highly conserved through all members of the ATXN7 gene family. The gene encoding ATXN7L2 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Ataxin-7-like protein 2; ATXN7L2
Swiss Prot
Q5T6C5
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human ATXN7L2
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 77 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ATXN7L2 polyclonal antibody detects endogenous levels of ATXN7L2 protein.
Applications Notes
Western blot (WB) analysis of ATXN7L2 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate
Host or Source
Rabbit

Related Products

CatalogName
BS61134-01ATXN7L1 polyclonal antibody
BS77197ATXN7L1 polyclonal antibody
BS65897-01ATXN3L Polyclonal Antibody
BS60839-01ATXN7 polyclonal antibody
BS76897-01ATXN2 polyclonal antibody
BZ16794-01Polyclonal antibodyPN1 polyclonal antibody
BS75206-01AaaaaASPH polyclonal antibody
BS5662-01CHST1 polyclonal antibody
BS71123-01COPS7A polyclonal antibody
BS65479-01GDN Polyclonal Antibody

Alternative Products

CatalogName
MBS9238390-01ATXN7L2 Polyclonal Antibody
NBP1-83876-25ulRabbit Polyclonal ATXN7L2 Antibody
TA337844ATXN7L2 Rabbit Polyclonal Antibody
TMAB-02969-01Anti-ATXN7L2 Polyclonal Antibody
bs-7976R-FITCATXN7L2 Polyclonal Antibody, FITC Conjugated
bs-7976R-Cy5ATXN7L2 Polyclonal Antibody, Cy5 Conjugated
GTR17755953ATXN7L2 Rabbit Polyclonal Antibody (HRP)
GTR18366064ATXN7L2 Rabbit Polyclonal Antibody (FITC)
GTR18366062ATXN7L2 Rabbit Polyclonal Antibody (Biotin)
MBS8109925-01Anti-ATXN7L2 Antibody, Rabbit Polyclonal

Popular Products