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STAC3 polyclonal antibody

CAT: 0384-BS60612-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS60612-01Size:50 µL
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Background
The Src homology 3 (SH3) domain is a highly conserved 60 amino acid protein domain that is organized into a beta-barrel fold consisting of five or six beta strands arranged as two tightly packed anti-parallel beta sheets. This domain is found in proteins that mediate assembly of specific protein complexes and interact with other proteins, specifically recognizing proline-rich regions. STAC3 (SH3 and cysteine rich domain 3) is a 364 amino acid protein containing one phorbol-ester/DAG-type zinc finger and two SH3 (Src homology 3) domains. Existing as two alternatively spliced isoforms, STAC3 maps to human chromosome 12q13.3. Human chromosome 12 encodes over 1,400 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
SH3 and cysteine-rich domain-containing protein 3; STAC3
Swiss Prot
Q96MF2
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human STAC3
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 42 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
STAC3 polyclonal antibody detects endogenous levels of STAC3 protein.
Applications Notes
Western blot (WB) analysis of STAC3 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:PC12 whole cell lysate
Host or Source
Rabbit

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