MRPL17 polyclonal antibody

CAT: 0384-BS60524-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS60524-01Size:50 µL
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Background
Mitochondria have their own translation machinery for production of thirteen proteins that are required for oxidative phosphorylation. MRP-L17 (39S ribosomal protein L17, mitochondrial), also known as LIP2 (LYST-interacting protein 2), is a 175 amino acid protein that is a component of the large ribosomal subunit of the mitochondria. Expressed in adipose tissue, adrenal gland and mammary gland, MRP-L17 is one of the 70 protein components of mitochondrial ribosomes that are encoded by the nuclear genome.The gene encoding MRP-L17 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
39S ribosomal protein L17, mitochondrial; L17mt; MRP-L17; LYST-interacting protein 2; MRPL17; LIP2
Swiss Prot
Q9NRX2
Reactivity
Human, Mouse
Immunogen
A synthetic peptide corresponding to residues in Human MRPL17
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 20 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
MRPL17 polyclonal antibody detects endogenous levels of MRPL17 protein.
Applications Notes
Western blot (WB) analysis of MRPL17 polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:Jurkat whole cell lysate
Host or Source
Rabbit

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