MRPL17 polyclonal antibody

• Background:

  Mitochondria have their own translation machinery for production of thirteen proteins that are required for oxidative phosphorylation. MRP-L17 (39S ribosomal protein L17, mitochondrial), also known as LIP2 (LYST-interacting protein 2), is a 175 amino acid protein that is a component of the large ribosomal subunit of the mitochondria. Expressed in adipose tissue, adrenal gland and mammary gland, MRP-L17 is one of the 70 protein components of mitochondrial ribosomes that are encoded by the nuclear genome.The gene encoding MRP-L17 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  39S ribosomal protein L17, mitochondrial; L17mt; MRP-L17; LYST-interacting protein 2; MRPL17; LIP2

• Swiss Prot:

  Q9NRX2

• Reactivity:

  Human, Mouse

• Immunogen:

  A synthetic peptide corresponding to residues in Human MRPL17

• Conjugation:

  Unconjugated

• Applications:

  WB

• Dilution:

  WB: 1:500~1:1000

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 20 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  MRPL17 polyclonal antibody detects endogenous levels of MRPL17 protein.

• Applications Notes:

  Western blot (WB) analysis of MRPL17 polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:Jurkat whole cell lysate

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4