CD42c polyclonal antibody

• Background :

  CD42a is a single-chain membrane glycoprotein that forms a noncovalent complex with CD42b. CD42b, also known as glycoprotein Ib a (GPIb a) is a membrane glycoprotein that is composed of a and b chains. The CD42b b chain is also designated CD42c, and is expressed on platelets and megakaryoctes. CD42a and CD42b are also present on platelets and mega-karyocytes, and the complex is a major component of the platelet surface. The complex acts as a receptor for von Willebrand’s factor and as a von Willebrand’s factor-dependent adhesion receptor.

• Structure Composition :

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  Platelet glycoprotein Ib beta chain; GP-Ib beta; GPIb-beta; GPIbB; Antigen CD42b-beta; CD42c; GP1BB

• Swiss Prot :

  P13224

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthetic peptide corresponding to residues in Human CD42c.

• Conjugation :

  Unconjugated

• Applications :

  WB

• Dilution :

  WB: 1:500~1:1000

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  ~ 22 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  CD42c polyclonal antibody detects endogenous levels of CD42c protein.

• Applications Notes :

  Western blot (WB) analysis of GP1BB polyclonal antibody at 1:500 dilution Lane1:Jurkat whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:Rat heart tissue lysate

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4