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SIN3B polyclonal antibody

CAT: 0384-BS5930-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS5930-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Paired amphipathic helix protein Sin3b; Histone deacetylase complex subunit Sin3b; Transcriptional corepressor Sin3b; KIAA0700
Swiss Prot
O75182
Reactivity
Human, Mouse
Immunogen
Synthetic peptide, corresponding to amino acids 260-305 of Human SIN3B.
Conjugation
Unconjugated
Applications
WB IF
Dilution
WB: 1:500~1:1000 IF: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 40, 129, 133 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
SIN3B polyclonal antibody detects endogenous levels of SIN3B protein.
Applications Notes
Western blot (WB) analysis of SIN3B polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:sp2/0 cell lysate
Host or Source
Rabbit

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