Products for Research Use Only
RegisterLogin

PKN1 polyclonal antibody

CAT: 0384-BS5859-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS5859-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Protein kinase N (PKN) is a fatty acid-activated serine/threonine kinase whose catalytic domain exhibits homology with that of the PKC family. PKN associates with Rho via its amino terminus, is activated in a GTP-dependent manner and phosphorylates the head-rod domain of neurofilament protein. A second protein, rhophilin, exhibits 40% sequence identity with the amino terminal Rho binding domain. The enzymatic activity of rhophilin has not been demonstrated and it is possible that it acts through the recruitment of cytoskeletal components that initiate a kinase signaling cascade. Citron interacts specifically with active Rho and Rac1 but not Cdc42. Citron exhibits a distinctive protein organization and little homology with the Rho binding domains of PKN and rhophilin.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Serine/threonine-protein kinase N1; Protease-activated kinase 1; PAK-1; Protein kinase C-like 1; Protein kinase C-like PKN; Protein kinase PKN-alpha; Protein-kinase C-related kinase 1; Serine-threonine protein kinase N; PAK1; PKN; PRK1; PRKCL1
Swiss Prot
Q16512
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 294-339 of Human PKN1.
Conjugation
Unconjugated
Applications
WB ICC
Dilution
WB: 1:500~1:1000 ICC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 103, 120 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
PKN1 polyclonal antibody detects endogenous levels of PKN1 protein.
Applications Notes
Western blot (WB) analysis of PKN1 polyclonal antibody at 1:500 dillution Lane1:MCF-7 whole cell lysate (40μg) Lane2:AML-12 whole cell lysate (40μg) Lane3:BV2 whole cell lysate (40μg) Lane4:C6 whole cell lysate (40μg) Lane5:H9C2 whole cell lysate (40μg)
Host or Source
Rabbit

Related Products

CatalogName
MB11431PKN1 monoclonal antibody
BS64582-01PKN1/2 (Phospho-T774/T816) polyclonal antibody
BS47693PKN1 Recombinant Rabbit mAb
BS46503-01PKN1 Recombinant Rabbit mAb
BS77687-01PRK2/PKN2 polyclonal antibody
BS41429-01PKN2 Rabbit monoclonal antibody
BS40036-01PKN2 Rabbit monoclonal antibody
BZ16794-01Polyclonal antibodyPN1 polyclonal antibody
BS75206-01AaaaaASPH polyclonal antibody
BS65563-01Mras polyclonal antibody

Alternative Products

CatalogName
MBS8529385-01PKN1 Polyclonal Antibody
NBP2-95113-0.1mLRabbit Polyclonal PKN1 Antibody
MBS9464327-01PKN1 Rabbit Polyclonal Antibody
HS811014-01Anti-PKN1 Polyclonal Antibody

Popular Products