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CD1E polyclonal antibody

CAT: 0384-BS5652-01Size: 50 µLDry Ice: NoHazardous: No
CAT#: BS5652-01Size: 50 µL
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD1E, also known as R2 or CD1A, is a 322 amino acid single-pass type I membrane protein that localizes to the lumen of the endoplasmic reticulum, as well as to the golgi apparatus, and contains one Ig-like domain. Expressed in a variety of tissues and on cortical thymocytes, dendritic cells and Langerhans cells, CD1E exists as a heterodimer with β-2-Microglobulin and is necessary for the presentation of glycolipid antigens on the cell surface. CD1E is subject to post-translational mono-ubiquitination and may also be proteolytically cleaved in endosomes to yield a soluble protein. CD1E is present on the surface of some T-cell leukemias, suggesting a possible role in tumorigenesis.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
T-cell surface glycoprotein CD1e, membrane-associated; hCD1e; R2G1; CD1e; T-cell surface glycoprotein CD1e, soluble; sCD1e
Swiss Prot
P15812
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 258-303 of Human CD1E.
Conjugation
Unconjugated
Applications
WB ICC
Dilution
WB: 1:500~1:1000 ICC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 44 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD1E polyclonal antibody detects endogenous levels of CD1E protein.
Applications Notes
Western blot (WB) analysis of CD1E polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:sp2/0 cell lysate Lane3:H9C2 cell lysate
Host or Source
Rabbit

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