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T2R1 (D45) polyclonal antibody

CAT: 0384-BS2964-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS2964-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The sense of taste is essential for the survival of organisms. For example, the ability to identify sweet-tasting foods enables animals to seek out food with high nutritive value, whereas the ability to identify bitter substances enables them to avoid the ingestion of potentially harmful substances. A family of integral membrane proteins are involved in taste perception and include T1R, which is involved in sweet taste perception and T2R, which is involved in bitter taste perception. Both types of taste receptors couple to various G proteins to initiate signal transduction cascades. Specifically, T2R1 is expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Taste receptor type 2 member 1; T2R1; Taste receptor family B member 7; TRB7; TAS2R1
Swiss Prot
Q9NYW7
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 12-60 of Human T2R1.
Conjugation
Unconjugated
Applications
WB IF
Dilution
WB: 1:500~1:1000 IF: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 33 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
T2R1 (D45) polyclonal antibody detects endogenous levels of T2R1 protein.
Applications Notes
Western blot (WB) analysis of T2R1 (D45) pAb at 1:500 dilution Lane1:K562 whole cell lysate (40ug) Lane2:MEF whole cell lysate (40ug) Lane3:HEK293T whole cell lysate (40ug) Lane4:C6 whole cell lysate (40ug)
Host or Source
Rabbit

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