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HoxD12 (E230) polyclonal antibody

CAT: 0384-BS2651-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS2651-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxD12 (homeobox D12), also known as HOX4H, is a 275 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. One of several members of the homeobox superfamily, HoxD12 functions as a sequencespecific transcription factor that is important for the correct positioning of developing limb buds on the anterior-posterior axis.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Homeobox protein Hox-D12; Homeobox protein Hox-4H; HOXD12; HOX4H
Swiss Prot
P35452
Reactivity
Human, Mouse
Immunogen
Synthetic peptide, corresponding to amino acids 200-250 of Human HoxD12.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 30 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
HoxD12 (E230) polyclonal antibody detects endogenous levels of HoxD12 protein.
Host or Source
Rabbit

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