GPR153 (E234) polyclonal antibody

• Background :

  G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR153 (G protein-coupled receptor 153), also known as PGR1, is a 609 amino acid multi-pass membrane protein that functions as an orphan receptor and belongs to the GPR1 family. The gene encoding GPR153 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

• Structure Composition :

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  Probable G-protein coupled receptor 153; PGR1

• Swiss Prot :

  Q6NV75

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthetic peptide, corresponding to amino acids 201-256 of Human GPR153.

• Conjugation :

  Unconjugated

• Applications :

  IHC IF

• Dilution :

  IHC: 1:50~1:200 IF: 1:50~1:200

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  ~ 65 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  GPR153 (E234) polyclonal antibody detects endogenous levels of GPR153 protein.

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4