LTβR (R44) polyclonal antibody

• Background:

  The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin alpha and lymphtoxin beta) . The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  Tumor necrosis factor receptor superfamily member 3; Lymphotoxin-beta receptor; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor type III; TNF-RIII; TNFR-III; D12S370; TNFCR; TNFR3; TNFRSF3; LTBR

• Swiss Prot:

  P36941

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide, corresponding to amino acids 20-60 of Human LTβR.

• Conjugation:

  Unconjugated

• Applications:

  WB IF

• Dilution:

  WB: 1:500~1:1000 IF: 1:50~1:200

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 50 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  LTβR (R44) polyclonal antibody detects endogenous levels of LTβR protein.

• Applications Notes:

  Western blot (WB) analysis of LTβR (R44) polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate (36ug) Lane2:RAW264.7 whole cell lysate (36ug) Lane3:PC12 whole cell lysate (36ug) Lane4:NIH-3T3 whole cell lysate (36ug) Lane5:HEK293T whole cell lysate (36ug)

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4