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FoxB1/2 (I72) polyclonal antibody

CAT: 0384-BS2130-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS2130-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
FKH5; forkhead box B2; Forkhead box protein B1; Forkhead box protein B2; Transcription factor FKH 5
Swiss Prot
Q99853/Q5VYV0
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 40-87 of Human FoxB1.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 35,46 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
FoxB1/2 (I72) polyclonal antibody detects endogenous levels of FoxB1/2 protein.
Applications Notes
Western blot (WB) analysis of FoxB1/2 (I72) pAb at 1:500 dilution Lane1:Myla2059 whole cell lysate (40ug) Lane2:Hela whole cell lysate (40ug) Lane3:SGC7901 whole cell lysate (40ug) Lane4:The Embryo tissue lysate of Mouse (40ug) Lane5:The Testis tissue lysate of Rat (10ug)
Host or Source
Rabbit

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