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GAS3 (A142) polyclonal antibody

CAT: 0384-BS1688-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS1688-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PMP 22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system. In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot Marie Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
PMP22; PMP-22; Growth arrest-specific protein 3; GAS-3; PMP22; GAS3 Growth Arrest Specific 3 HNPP Peripheral Myelin Protein 22 Trembler
Swiss Prot
Q01453
Reactivity
Human, Mouse
Immunogen
Synthetic peptide, corresponding to amino acids 120-170 of Human GAS3.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 22 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GAS3 (A142) polyclonal antibody detects endogenous levels of GAS3 protein.
Applications Notes
Western blot (WB) analysis of GAS3 (A142) pAb at 1:500 dilution Lane1:MCF-7 whole cell lysate (40ug) Lane2:H1792 whole cell lysate (40ug) Lane3:A2780 whole cell lysate (40ug) Lane4:HCT116 whole cell lysate (40ug) Lane5:PC3 whole cell lysate (40ug) Lane6:PMVEC whole cell lysate (40ug) Lane7:CT-26 whole cell lysate (40ug)
Host or Source
Rabbit

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