APC1 (E684) polyclonal antibody

CAT: 0384-BS1611-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS1611-01Size:50 µL
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Background
APC1 is 1 of at least 11 subunits of the anaphase promoting complex (APC), which functions at the metaphase to anaphase transition of the cell cycle and is regulated by spindle checkpoint proteins. The APC is an E3 ubiquitin ligase that targets cell cycle regulatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Anaphase-promoting complex subunit 1; APC1; Cyclosome subunit 1; Mitotic checkpoint regulator; Testis-specific gene 24 protein; ANAPC1; TSG24
Swiss Prot
Q9H1A4
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 650-698 of Human APC1.
Conjugation
Unconjugated
Applications
WB IHC IF
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
APC1 (E684) polyclonal antibody detects endogenous levels of APC1 protein.
Applications Notes
Western blot (WB) analysis of APC1 (E684) polyclonal antibody at 1:500 dilution Lane1:A549 whole cell lysate (40ug) Lane2:SGC7901 whole cell lysate (40ug) Lane3:BV2 whole cell lysate (40ug) Lane4:HCT116 whole cell lysate (40ug) Lane5:PC12 whole cell lysate (40ug)
Host or Source
Rabbit

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