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PYK2 (I574) polyclonal antibody

CAT: 0384-BS1420-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS1420-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Pyk2 is a protein tyrosine kinase related to Focal Adhesion Kinase (p125 FAK) . Pyk2 is highly expressed in the central nervous system. It is phosphorylated on tyrosine residues in response to various stimuli that elevate intracellular calcium concentration, as well as by protein kinase C activation.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Cell adhesion kinase beta; CAK beta; Calcium-dependent tyrosine kinase; CADTK; Related adhesion focal tyrosine kinase; RAFTK; PYK2; FAK2; PYK2; RAFTK
Swiss Prot
Q14289
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 360-418 of Human TFDP1.
Conjugation
Unconjugated
Related Pathways
G Protein-coupled Receptors Signaling to MAPK Erk, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 115 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
PYK2 (I574) polyclonal antibody detects endogenous levels of PYK2 protein.
Applications Notes
Western blot (WB) analysis of PYK2 (I574) pAb at 1:500 dilution Lane1:K562 whole cell lysate (40ug) Lane2:A549 whole cell lysate (40ug) Lane3:Hela whole cell lysate (40ug) Lane4:The Brain tissue lysate of Mouse (40ug) Lane5:The Brain tissue lysate of Rat (40ug)
Host or Source
Rabbit

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