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PYK2 monoclonal antibody

CAT: 0384-MB66631-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-MB66631-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Protein tyrosine kinase Pyk2, also called CAKβ, RAFTK and CADTK, is a nonreceptor tyrosine kinase structurally related to focal adhesion kinase (FAK) . Pyk2 is predominantly expressed in cells derived from hematopoietic lineages and in the central nervous system. Pyk2 is one of the signaling mediators for the G-protein-coupled receptors and MAP kinase signaling pathway. It plays an important role in cell spreading and migration.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Proline-rich tyrosine kinase 2; Related adhesion focal tyrosine kinase; RAFTK
Swiss Prot
Q14289
Reactivity
Human
Immunogen
Purified recombinant fragment of PYK2 (aa815-997) expressed in E. Coli.
Conjugation
Unconjugated
Related Pathways
G-Protein-Coupled Receptors Signaling to MAPK/Erk, MAPK/Erk in Growth and Differentiation.
Applications
WB, IHC
Dilution
WB (1/500 - 1/1000), IHC (1/50 - 1/100)
Purity
The antibody was purified by immunogen affinity chromatography.
Modification
Unmodification
Molecular Weight
~ 116 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of PYK2 protein.
Applications Notes
Western blot analysis of PYK2 expression in A549 (A), Ramos (B), Jurkat (C), THP1 (D), Raji (E) whole cell lysates.
Host or Source
Mouse

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