Products for Research Use Only
RegisterLogin

C-Jun (G237) polyclonal antibody

CAT: 0384-BS1058-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS1058-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE) . Two additional genes, Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
JUN; p39; V-jun avian sarcoma virus 17 oncogene homolog; Proto-oncogene c-Jun; AP1; Activator protein 1; Transcription factor AP-1
Swiss Prot
P05412
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 201-250 of Human c-Jun.
Conjugation
Unconjugated
Related Pathways
MAPK Erk in Growth and Differentiation Pathway
Applications
WB IHC IP
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200 IP: 1:10~1:100
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~36, 43, 48 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
C-Jun (G237) polyclonal antibody detects endogenous levels of c-Jun protein.
Applications Notes
Western blot (WB) analysis of c-Jun (G237) pAb at 1:500 dilution Lane1:CT26 whole cell lysate (40ug) Lane2:H9C2 whole cell lysate (40ug) Lane3:HEK293T whole cell lysate (40ug) Lane4:MCF-7 whole cell lysate (40ug) Lane5:A549 whole cell lysate (40ug)
Host or Source
Rabbit

Related Products

CatalogName
BZ16424c-Jun polyclonal antibody
BS80097c-Jun polyclonal antibody
BS6436c-Jun polyclonal antibody
BS90305c-Jun polyclonal antibody
BZ16535c-Jun polyclonal antibody
BS79651-01C-Jun polyclonal antibody
BS1057-01C-Jun (P233) polyclonal antibody
BS1060-01C-Jun (G67) polyclonal antibody
BS1056c-Jun (H164) polyclonal antibody
BS1528c-Jun (I245) polyclonal antibody

Alternative Products

CatalogName
GTR18040920-01C-Jun (G237) polyclonal antibody
APR02590GPolyclonal JUN / c-Jun Antibody
TA384582c-Jun (JUN) Rabbit Polyclonal Antibody
GTR18087286C-Jun/JUN Rabbit Polyclonal Antibody

Popular Products