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CD160 (T45) polyclonal antibody

CAT: 0384-BS2217-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS2217-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD160, also known as NK1, BY55 or NK28, is a 181 amino acid lipid-anchored cell membrane glycoprotein that contains one immunoglobulin-like domain. Expressed in small intestine, spleen and functional NK (natural killer) and T cytotoxic lymphocytes, CD160 exists as a disulfide-linked homomultimer that functions as a receptor for MHC (major histocompatability complex) molecules and is thought to regulate the function of NK cells. Additionally, CD160 interacts with HVEM (herpesvirus entry mediator) and, via this interaction, is able to negatively regulate CD4+ T cell activation, indicating a role in immune system regulation. Multiple isoforms of CD160 exist due to alternative splicing events. The gene encoding CD160 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
CD160 antigen; Natural killer cell receptor BY55; CD160; CD160; BY55
Swiss Prot
O95971
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 21-70 of Human CD160.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 19 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD160 (T45) polyclonal antibody detects endogenous levels of CD160 protein.
Applications Notes
Western blot (WB) analysis of CD160 pAb at 1:1000 dilution Lane1:RAW264.7 whole cell lysate (40ug) Lane2:K562 whole cell lysate (40ug) Lane3:Jurkat whole cell lysate (40ug) Lane4:Myla2059 whole cell lysate (40ug)
Host or Source
Rabbit

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