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CD160 polyclonal antibody

CAT: 0384-NCP0181P-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-NCP0181P-01Size:50 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
CD160 antigen; BY55; Natural killer cell receptor BY55
Swiss Prot
O95971
Reactivity
Human, Rat, Mouse
Immunogen
Recombinant protein of human CD160.
Conjugation
Unconjugated
Applications
IF
Dilution
IF: 1:200~1:800
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD160 polyclonal antibody detects endogenous levels of CD160 protein.
Applications Notes
Immunofluorescence analysis of MG63 cells using CD160 pAb at dilution of 1:400 (40x lens) .
Host or Source
Rabbit

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Alternative Products

CatalogName
MBS2520083-01CD160 Polyclonal Antibody
APR06839GPolyclonal CD160 Antibody

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